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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GEM
All Species:
30.91
Human Site:
S245
Identified Species:
68
UniProt:
P55040
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55040
NP_005252.1
296
33949
S245
Q
V
R
L
R
R
D
S
K
E
K
N
E
R
R
Chimpanzee
Pan troglodytes
XP_001142135
295
33821
S245
Q
V
R
L
R
R
D
S
K
E
K
N
E
R
R
Rhesus Macaque
Macaca mulatta
XP_001087974
295
33787
S244
Q
V
R
L
R
R
D
S
K
E
K
N
E
R
R
Dog
Lupus familis
XP_854414
517
56511
S466
Q
V
R
L
R
R
D
S
K
E
K
N
E
R
R
Cat
Felis silvestris
Mouse
Mus musculus
P55041
295
33707
S244
Q
V
R
L
R
R
D
S
K
E
K
N
E
R
R
Rat
Rattus norvegicus
P55043
306
33020
S255
Q
I
R
L
R
R
D
S
K
E
D
N
A
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515756
162
18547
K123
A
R
R
M
A
N
T
K
R
R
E
S
I
G
K
Chicken
Gallus gallus
NP_998744
297
34218
S246
Q
V
R
L
R
R
D
S
K
E
K
N
E
K
R
Frog
Xenopus laevis
Q6IP71
206
23374
K167
K
T
R
A
N
V
D
K
V
F
F
D
L
M
R
Zebra Danio
Brachydanio rerio
NP_956092
300
34100
S249
Q
I
R
L
R
K
D
S
K
E
E
N
A
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48555
201
22920
D162
A
K
T
R
E
N
V
D
K
V
F
F
D
L
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.3
54.1
N.A.
95.6
53.2
N.A.
44.5
82.4
26.3
59.6
N.A.
26.6
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
99.3
55.3
N.A.
97.6
68.3
N.A.
50
92.9
44.5
75
N.A.
41.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
80
N.A.
6.6
93.3
20
73.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
86.6
N.A.
40
100
33.3
93.3
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
10
10
0
0
0
0
0
0
0
19
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
82
10
0
0
10
10
10
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
73
19
0
55
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
19
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
19
0
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
10
10
0
0
0
10
0
19
82
0
55
0
0
10
10
% K
% Leu:
0
0
0
73
0
0
0
0
0
0
0
0
10
10
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
10
% M
% Asn:
0
0
0
0
10
19
0
0
0
0
0
73
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
73
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
91
10
73
64
0
0
10
10
0
0
0
64
82
% R
% Ser:
0
0
0
0
0
0
0
73
0
0
0
10
0
0
0
% S
% Thr:
0
10
10
0
0
0
10
0
0
0
0
0
0
0
0
% T
% Val:
0
55
0
0
0
10
10
0
10
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _